MicroRNAs in Pediatric Cholestatic Liver Diseases: Molecular Regulation, Diagnostic Biomarkers, and Therapeutic Perspectives

Authors

  • Ahmed Hamdy Rezk Al Agamy , Hatem Mohammed Hussein , Behery El Sayed Behery , Adel Sherif Ahmed , Samar Ibrahim Ghanem

Keywords:

microRNAs, neonatal cholestasis, biliary atresia, circulating biomarkers

Abstract

Background: Infantile cholestatic liver disease develops within a rapidly changing regulatory environment, yet tissuespecific molecular signals are difficult to interpret and have not entered routine diagnosis. Objective: To critically integrate evidence available through 2024 while identifying mechanisms

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References

Cheng G, Tang CS, Wong EH, et al. Common genetic variants regulating ADD3 gene expression alter biliary atresia risk. J Hepatol.

;59(6):1285-91.

Hellen DJ, Karpen SJ. Genetic contributions to biliary atresia: a developmental cholangiopathy. Semin Liver Dis. 2023;43(4):458-469.

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Published

2024-03-20

How to Cite

Ahmed Hamdy Rezk Al Agamy , Hatem Mohammed Hussein , Behery El Sayed Behery , Adel Sherif Ahmed , Samar Ibrahim Ghanem. (2024). MicroRNAs in Pediatric Cholestatic Liver Diseases: Molecular Regulation, Diagnostic Biomarkers, and Therapeutic Perspectives. Pegem Journal of Education and Instruction, 14(3), 1355–1363. Retrieved from https://www.pegegog.net/index.php/pegegog/article/view/5350

Issue

Vol. 14 No. 3 (2024): PEGEGOG

Section

Article

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