Renal Involvement in Inflammatory Bowel Disease: Pathogenesis, Clinical Spectrum, and Management Strategies

Authors

  • Ezzat Mostafa Mohamed, Said M Al-Barshomy, Sameh Abou Zeid, Mai Mohamed Abdelwahab, Abdallah Mahmoud Mohamed Mohamed

Keywords:

Renal Involvement, Inflammatory Bowel Disease, Management Strategies

Abstract

Renal involvement in inflammatory bowel disease (IBD) is an underrecognized yet clinically relevantextraintestinal manifestation. Affecting both Crohn’s disease (CD) and ulcerative colitis (UC), renal complicationsencompass glomerular disorders, tubulointerstitial nephritis, nephrolithiasis, amyloidosis, and drug-induced injury. Themechanisms underlying renal involvement are multifactorial, including immune dysregulation, systemic inflammation,metabolic disturbances, surgical consequences,

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References

Vavricka SR, Rogler G, Gantenbein C, Spoerri M, Prinz Vavricka BM, Navarini AA, French LE. Extraintestinal manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2015;21(8):1982-1992.

Said SM, Nasr SH. Renal manifestations of inflammatory bowel disease. Semin Nephrol. 2015;35(5):436-446.

Weng MT, Chiu YT, Wei SC. Mechanisms of inflammatory bowel disease-related extra-intestinal manifestations. J Gastroenterol Hepatol. 2016;31(3):389-394

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Published

2024-03-20

How to Cite

Ezzat Mostafa Mohamed, Said M Al-Barshomy, Sameh Abou Zeid, Mai Mohamed Abdelwahab, Abdallah Mahmoud Mohamed Mohamed. (2024). Renal Involvement in Inflammatory Bowel Disease: Pathogenesis, Clinical Spectrum, and Management Strategies. Pegem Journal of Education and Instruction, 14(3), 654–665. Retrieved from https://www.pegegog.net/index.php/pegegog/article/view/4230

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