Renal Involvement in Inflammatory Bowel Disease: Pathogenesis, Clinical Spectrum, and Management Strategies
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Renal Involvement, Inflammatory Bowel Disease, Management StrategiesAbstract
Renal involvement in inflammatory bowel disease (IBD) is an underrecognized yet clinically relevantextraintestinal manifestation. Affecting both Crohn’s disease (CD) and ulcerative colitis (UC), renal complicationsencompass glomerular disorders, tubulointerstitial nephritis, nephrolithiasis, amyloidosis, and drug-induced injury. Themechanisms underlying renal involvement are multifactorial, including immune dysregulation, systemic inflammation,metabolic disturbances, surgical consequences,
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Weng MT, Chiu YT, Wei SC. Mechanisms of inflammatory bowel disease-related extra-intestinal manifestations. J Gastroenterol Hepatol. 2016;31(3):389-394
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